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Cannabidiol (CBD) in the Treatment of Cerebral Malaria

Cannabidiol (CBD) in the Treatment of Cerebral Malaria

Infections cause neurological problems such as attacking the memory center (hippocampus), cognition etc. This study shows how the parasite responsible for malaria affects the brain and how CBD can remedy this situation.

Here is an excerpt

Study Results

5 days post-infection, mice infected with the parasite and not treated cannabidiol (CBD) experienced:
  • memory dysfunction
  • an increase in anxiety-like behaviors
  • an increase in inflammatory markers TNF-α and IL-6 in the hippocampus
  • an increase in inflammatory marker IL-6 in the prefrontal cortex
However, 5 days post-infection, mice infected with the parasite and treated with cannabidiol (CBD), experienced:
  • no memory dysfunction
  • an increase in BDNF (acts to protect neurons, cells of the nervous system) in the hippocampus
  • a decrease in inflammatory marker TNF-α in the hippocampus
  • a decrease in inflammatory marker IL-6 in the pre-frontal cortex
Both Artesunate-only and CBD+Artesunate treatments resulted in decreases in anxiety-like behavior.

https://www.medicaljane.com/2015/01/26/cannabidiol-in-the-treatment-of-cerebral-malaria/ via @medicaljane

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