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Intestinal Barrier Efficiency (Metabolic Diseases)

 Frontiers | Enhancing intestinal barrier efficiency: A novel metabolic diseases therapy (frontiersin.org)


The intestinal tract is a complex organism, and the barrier function is now recognized as an important component of intestinal health. Barrier function is important for microbiome health and in particular, butyrate production. Butyrate is a short chain fatty acid which has systemic attributes. 

There are a number of factors that can reduce barrier integrity such as food-borne chemicals, pathogenic organisms, improper diet, high insulin production, all which will all lead to barrier weakness.  These all induce inflammatory cytokines which cause major problems in the body. This turns into a vicious cycle., 


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