Skip to main content

Multi Drug Resistance - 5 Extracts Tested

Antibiotic Resistance research is an ongoing area of interest. Research is continuing to evolve trying the unravel the mystery of MDR bacteria. Some research is linking DNA constructs while others are viewing the mechanisms of resistance such as efflux pumps.

There have been a whole host of articles reviewing nature's chemicals (polyphenols) for their ability to crack this code. There have been published studies on the role of using certain polyphenols in conjunction with antibiotics. 

This article is written from an Ayurvedic perspective. Ayurvedic medicine has a long history on the use of botanicals to solve health issues as any indigenous culture has. They (Ayur-Veda) have a large arsenal to look at. 

This article examines 5 well known botanicals that have been proven in other articles to show inhibition of MDR bacteria. Ceylon Cinnamon, Arjuna, Cloves, Acacia Nilotica and Eucalyptus are examined. Ethanol extracts are used. 

 Antimicrobial Activity of Five Herbal Extracts Against Multi Drug Resistant (MDR) Strains of Bacteria and Fungus of Clinical Origin - PMC (nih.gov)

Conclusions

The ethanolic extracts of A. nilotica, C. zeylanicum and S. aromaticum could be a possible source to obtain new and effective herbal medicines to treat infections caused by multi-drug resistant strains of microorganisms from community as well as hospital settings. However, it is necessary to determine the toxicity of the active constituents, their side effects and pharmaco-kinetic properties.

Comments

Post a Comment

Popular posts from this blog

Patrick Gut Environment

\ Keywords to use in further research, GALT, tight junction proteins, Mucin layer, microbiome in MECFS or Long Covid, Goblet cells.   It was great chatting with you the other day. I’ve put together this general overview, but as I mentioned, you’ll definitely want to do your own deeper research. This is a very complex, interactive environment, and you’ll naturally come across many different opinions about what’s happening. Most opinions tend to focus on single layers, but as I’ve discovered, these layers are highly interconnected and influence one another. I don’t want to oversimplify things, nor do I want to overcomplicate them. It takes time to truly understand the gut environment in its proper context. I’m also cautious about saying “do X and you’ll get Y,” because results are rarely that straightforward. When I introduce layered therapies, I look for subtle changes across a list of markers I track. That’s why I believe this should be approached with care and patience—though I’m ...
Post a Comment
Read more

Paneth Cells - guardians of the intestinal tract

  Click for the AI slideshow: https://sl.bing.net/hBioK3sTdDw From Google Gemini: Paneth Cells: The Guardians of the Gut Paneth cells are specialized epithelial cells found at the base of the intestinal crypts (small invaginations in the intestinal lining). They play a crucial role in maintaining the gut's health by acting as a first line of defense against harmful microorganisms. Key Functions: Antimicrobial Defense: Paneth cells produce and secrete a variety of antimicrobial peptides and proteins, such as lysozyme, defensins, and phospholipase A2. These substances help to kill bacteria, fungi, and other pathogens that may invade the intestinal tract. Regeneration of Intestinal Epithelium: Paneth cells contribute to the maintenance and regeneration of the intestinal lining by supporting the stem cells located nearby. Immune Regulation: These cells participate in regulating the immune response within the gut, helping to balance the body's reaction to both beneficial and ha...
Post a Comment
Read more

Gut environment

 OK let's go back over the scenario Somebody gets a gut bug that could be viral or bacterial and we're going to put in the context of either long COVID or MECFS Let's discuss what exactly happens of how the body begins to adapt to this insult p — let’s build this cleanly, structurally, and without drama. This is the core terrain‑mechanics model of what happens when someone gets a gut bug (viral or bacterial) and then develops a long‑tail condition like long COVID or ME/CFS . This is the architecture that explains why the system never fully resets . I’ll walk you through it in chronological order , layer by layer, so you can see exactly how the body adapts — and why those adaptations become the trap. ⭐ 1. The Initial Insult Terrain layer: immune activation, epithelial irritation, redox stress A viral or bacterial gut infection does three things immediately: damages epithelial cells strips mucin spikes inflammatory cytokines This creates: redox collapse increased permeabil...
Post a Comment
Read more