Research Articles

 Credit phys.org University of Chicago Credit: Nature Microbiology (2024). DOI: 10.1038/s41564-023-01560-2 © Provided by Phys.org T he gut microbiome is so useful to human digestion and health that it is often called an extra digestive organ. This vast collection of bacteria and other microorganisms in the intestine helps us break down foods and produce nutrients or other metabolites that impact human health in a myriad of ways. He Gets Us - Learn a Different Perspective Ad HeGetsUs New research from the University of Chicago shows that some groups of these microbial helpers are amazingly resourceful too, with a large repertoire of genes that help them generate energy for themselves and potentially influence human health as well. The paper,  published  January 4, 2024, in  Nature Microbiology , identified 22 metabolites that three distantly related families of gut bacteria use as alternatives to oxygen for respiration in the anaerobic environment of the gut. The...

  >Educational material only, this is not a diagnosis or treatment advice. Discuss this with your healthcare provider>>>>>>> Here are generalized notes, this is a short list, I will add more later. Here are some of the things that Nick (and myself) did: Vitamin D -  Vitamin A - the orphan vitamin that modulates the immune response. Selenium - another forgotten nutrient that plays a key role in Immunity. Polyphenols (PP): PP are powerful medicines. They do multiple functions such as helping your body cope with stress, they are powerful antioxidants, they can kill off bad bugs, they help the gut (microbiome), kill cancer cells etc.  Plants make these chemicals, example: green tea, basil, turmeric, ginger etc.  There are thousands of PP Some plants have more concentration of PP. We buy them from trusted sources (Frontier or Banyan) in bulk (saves money) they are organic. We use a wide spectrum of rich plants that are rich in PP. Things like turme...

Tight Junctions protect the intestinal complex - good tight junctions stop inflammation. This article discusses some of the roles of nutrients in creating good tight junctions. This includes polyphenols, sugars, fats, proteins, vitamins and minerals. Great article. Quercetin, Resveratrol (pterostilbene), naringenin (Citrus Grapefruit),  Naringenin,daidzein, hesperetin, morin, and myricetin enhance the integrity of the TJ barrier, whereas chrysin decreases TJ integrity (Noda,   Regulation of the intestinal barrier by nutrients: The role of tight junctions - PMC (nih.gov) Looks like dietary fiber can play a significant role in SCFA since it helps proliferate beneficial bacteria. Previous studies also found that there was a correlation between mucosal gene expression levels and SCFA concentration. Butyrate-producing bacteria ( Fusobacteria ) were positively correlated with tight junction protein (ZO-1) expression levels. Acetate, propionate, caproate, and branched-chain fatty aci...