CFS - How Immunity Influences Bad

Hypothesis Predicts Major Failure Point in Chronic Fatigue Syndrome (ME/CFS) - Health Rising

They proposed that two factors – sympathetic nervous system hyperactivity and ß2AdR receptor problems – are knocking the blood vessels of people with ME/CFS for a loop. As sympathetic nervous system hyperactivity is giving them a good squeeze, the ß2AdR receptors which are supposed to open them up are getting hammered by the immune system.

That leaves the blood vessels unable to deliver the proper amounts of blood to the muscles, brain, organs, etc. The body, of course, can’t have that and so it attempts to fix the situation by releasing vasodilators like bradykinin and prostaglandins.

The authors believe these vasodilators spill over into the bloodstream where they, alas, produce fatigue, pain, and flu-like symptoms as well as headaches, gut pain, cognitive and sleep problems.

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Paneth Cells - guardians of the intestinal tract

Click for the AI slideshow: https://sl.bing.net/hBioK3sTdDw From Google Gemini: Paneth Cells: The Guardians of the Gut Paneth cells are specialized epithelial cells found at the base of the intestinal crypts (small invaginations in the intestinal lining). They play a crucial role in maintaining the gut's health by acting as a first line of defense against harmful microorganisms. Key Functions: Antimicrobial Defense: Paneth cells produce and secrete a variety of antimicrobial peptides and proteins, such as lysozyme, defensins, and phospholipase A2. These substances help to kill bacteria, fungi, and other pathogens that may invade the intestinal tract. Regeneration of Intestinal Epithelium: Paneth cells contribute to the maintenance and regeneration of the intestinal lining by supporting the stem cells located nearby. Immune Regulation: These cells participate in regulating the immune response within the gut, helping to balance the body's reaction to both beneficial and ha...

Hi Holly's Daughter

Here are some general notes of the education I had in the Gut Environment. Keep in mind that this is educational and not a directive to treatment or diagnosis. As a side note, I spent an inordinate amount of time in this pursuit based on my own situation. I went to countless doctors and specialists to "resolve" my issues with little to no help. I personally have done these therapies countless times. I also hosted a forum on protozoa parasites and dives into antibiotic resistance. I did many stool samples (microbiology) to detect what bug I had contracted and did many therapies including antibiotics, probiotics and the like. Here is what I know. The Gastrointestinal Tract: The GI system is rather a complex organism that has many features that Western Medicine is just acknowledging at this point. The GI tract houses 70% of the immune response and these immune responses can react to both pathogens that enter the gut but also systemic infections (example a viral infection). In ...

Critters

I am going off the abundance of research articles that are now coming forward from researchers concerning the gut. 1. There are many species of organisms that live in your gut. 2. Everyone has different compositions. >New studies are showing a healthy microbiome translates to better metabolic numbers. They know that the healthy bacteria produce healthy byproducts that affect other systems (blood pressure, Metabolic X syndrome etc.) 3. The microbiome of the gut is formed by a multitude of factors such as age, sex, genetic predispositions, environmental chemicals and diet. 4. The concept of diet is largely outdated. What they should be focused on is feeding your healthy bacteria. 5. These organisms are many but likely could be grouped into segments. In other words, bacteria are not necessarily alike. 6. Bacteria like foods and by foods, I mean the chemicals that are found in the foods. 7. Polysaccharides are a meal for many bacteria and there are lots of polysac...

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